Publications

Roe E, Khov E, Kim H, Demelo B, Zavitz S, Cao-Lei L*. The impact of climate change-related disasters on mental health and epigenetics: a narrative review. Front. Epigenet. Epigenom. 2024 Sept Accepted.

Cao-Lei L, Saumier D, Fortin J, Brunet A. A narrative review of the epigenetics of post-traumatic stress disorder and post-traumatic stress disorder treatment. Front Psychiatry. 2022 Nov 7;13:857087. doi: 10.3389/fpsyt.2022.857087. PMID: 36419982; PMCID: PMC9676221

Cao-Lei L, van den Heuvel MI, Huse K, Platzer M, Elgbeili G, Braeken MAKA, Otte RA, Witte OW, Schwab M, Van den Bergh BRH. Epigenetic Modifications Associated with Maternal Anxiety during Pregnancy and Children's Behavioral Measures. cells. 2021 Sep 14;10(9):2421. doi: 10.3390/cells10092421. 

Cao-Lei L, Yogendran S, Dufoix R, Elgbeili G, Laplante PL, King S. Prenatal Maternal Stress from a Natural Disaster and Hippocampal Volumes: Gene-by-Environment Interactions in Young Adolescents from Project Ice Storm. Frontiers in Behavioral Neuroscience. 2021 DOI: 10.3389/fnbeh.2021.706660.

Derksen A, Mirchi A, Tran LT, Cao-Lei L, Oskoui M, Srour M, Poulin C; Care4Rare Canada Consortium, Bernard G. A Novel De Novo Variant in DYNC1H1 Causes Spinal Muscular Atrophy Lower Extremity Predominant in Identical Twins: A Case Report. Child Neurol Open. 2021 Jul 23;8:2329048X211027438. doi: 10.1177/2329048X211027438. 

Cherif LS, Cao-Lei L, Farinelle S, Muller CP, Turner JD, Schroeder H, Grova N. Assessment of 9-OH- and 7,8-diol-benzo[a]pyrene in Blood as Potent Markers of Cognitive Impairment Related to benzo[a]pyrene Exposure: An Animal Model Study. Toxics. 2021 Mar 8;9(3):50. doi: 10.3390/toxics9030050. PMID: 33800341; PMCID: PMC7998639.

Cao-Lei L, Elgbeili G, Laplante PL, Szyf M, King S. (2019) Differential genome-wide DNA methylation patterns in childhood obesity: Project Ice Storm. BMC Research Notes. 25;12(1):174. doi: 10.1186/s13104-019-4189-0.

Laplante DP, Simcock G, Cao-Lei L, Mouallem M, Elgbeili G, Brunet A, Cobham V, Kildea S, King S. (2018) The 5-HTTLPR polymorphism of the serotonin transporter gene and child sex moderate the relationship between disaster-related prenatal maternal stress and autism spectrum disorder traits: the QF2011 Queensland Flood Study. Development & Psychopathology. 31, 1395-1409.

Cao-Lei L, Dancause KN, Elgbeili G, Laplante DP, Szyf M, King S. (2018) DNA methylation mediates the effect of maternal cognitive appraisal of a disaster in pregnancy on the child's C-peptide secretion in adolescence: Project Ice Storm. PLoS One. 5;13(2):e0192199.

Cao-Lei L, De Rooij SR, King S, Matthews S, Metz GAS, Roseboom TJ, Szyf M. (2017) Prenatal Stress and Epigenetics. Neurosci Biobehav Rev. 117:198-210. doi: 10.1016/j.neubiorev.2017.05.016. Epub 2017 May 18.

Cao-Lei L, Dancause KN, Elgbeili G, Szyf M, Laplante DP, King S. (2016) Pregnant women’s cognitive appraisal of a natural disaster affects their children’s BMI and central adiposity via DNA methylation: Project Ice Storm. Early Human development. 103:189-192.

Cao-Lei L, Veru F, Elgbeili G, Szyf M, Laplante DP, King S (2016) DNA methylation mediates the effect of exposure to prenatal maternal stress on cytokine production in children at age 13½ years: Project Ice Storm. Clinical Epigenetics. 12;8:54.

Cao-Lei L, Laplante DP, King S (2016) Prenatal Maternal Stress and Epigenetics: Review of the Human Research. Curr Mol Bio Rep. 2:16–25. DOI 10.1007/s40610-016-0030-x.

Cao-Lei L, Dancause KN, Elgbeili G, Massart R, Szyf M, Liu A, Laplante DP, King S (2015) DNA methylation mediates the impact of exposure to prenatal maternal stress on BMI and central adiposity in children at age 13½ years: Project Ice Storm. Epigenetics. Aug 3;10(8):749-61.

Cao-Lei L, Elgbeili G, Massart R, Laplante DP, Szyf M, King S (2015) Pregnant women’s cognitive appraisal of a natural disaster affects DNA methylation in their children 13 years later: Project Ice Storm. Translational Psychiatry. 5:e515. 

Cao-Lei L, Massart R, Suderman MJ, Machnes Z, Elgbeili G, Laplante DP, Szyf M, King S (2014) DNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: Project Ice Storm. PLoS One. 19;9(9):e107653. 

Cao-Lei L, Suwansirikul S, Jutavijittum P, Mériaux SB, Turner JD, Muller CP (2013) Glucocorticoid receptor gene expression and promoter CpG modifications throughout the human brain. J Psychiatr Res. 47(11):1597-607. 

Cao-Lei L, Leija SC, Kumsta R, Wust S, Meyer J, Turner JD, Muller CP (2011) Transcriptional control of the human glucocorticoid receptor: identification and analysis of alternative promoter regions. Hum Genet 129: 533-43.

Turner JD, Alt SR, Cao L, Vernocchi S, Trifonova S, Battello N, Muller CP (2010) Transcriptional control of the glucocorticoid receptor: CpG islands, epigenetics and more. Biochem Pharmacol 80: 1860-1868.

Cao L, Grova N, Muller PC, Schroeder H. Effects of an oral subacute administration of benzo(a)pyrene on cerebral CYP1A1 expression and anxiety-related behaviour in adult mice. Toxicology Letters. 180S (2008) S32–S246