2024

Ravel-Chapuis A, Fahmi C, Gobin J, Jasmin BJ. The AMPK allosteric activator MK-8722 improves the histology and spliceopathy in myotonic dystrophy type 1 (DM1) skeletal muscle. FASEB J. 2024 Dec 15;38(23):e70199. doi: 10.1096/fj.202401145RR. PMID: 39611312.

Roussel MP, Ravel-Chapuis A, Gobin J, Jasmin BJ, Leduc-Gaudet JP, Gagnon C, Duchesne E. Changes in Physiopathological Markers in Myotonic Dystrophy Type 1 Skeletal Muscle: A 3-Year Follow-up Study. J Neuromuscul Dis. 2024;11(5):981-995. doi: 10.3233/JND-230139. PMID: 39031377; PMCID: PMC11380274.

2023

Neault N, Ravel-Chapuis A, Baird SD, Lunde JA, Poirier M, Staykov E, Plaza-Diaz J, Medina G, Abadía-Molina F, Jasmin BJ, MacKenzie AE. Vorinostat Improves Myotonic Dystrophy Type 1 Splicing Abnormalities in DM1 Muscle Cell Lines and Skeletal Muscle from a DM1 Mouse Model. Int J Mol Sci. 2023 Feb 14;24(4):3794. doi: 10.3390/ijms24043794. PMID: 36835205; PMCID: PMC9964082.

2022

Osseni A*, Ravel-Chapuis A*, Belotti E, Scionti I, Gangloff YG, Moncollin V, Mazelin L, Mounier R, Leblanc P, Jasmin BJ, Schaeffer L. Pharmacological inhibition of HDAC6 improves muscle phenotypes in dystrophin-deficient mice by downregulating TGF-β via Smad3 acetylation. Nat Commun. 2022 Nov 19;13(1):7108. doi: 10.1038/s41467-022-34831-3. PMID: 36402791; PMCID: PMC9675748.

Misquitta NS, Ravel-Chapuis A*, Jasmin BJ*. Combinatorial treatment with exercise and AICAR potentiates the rescue of myotonic dystrophy type 1 mouse muscles in a sex-specific manner. Hum Mol Genet. 2023 Jan 27;32(4):551-566. doi: 10.1093/hmg/ddac222. PMID: 36048859.

Freeman E, Langlois S, Scott K, Ravel-Chapuis A, Jasmin BJ, Cowan KN. Sex-dependent role of Pannexin 1 in regulating skeletal muscle and satellite cell function. J Cell Physiol. 2022 Oct;237(10):3944-3959. doi: 10.1002/jcp.30850. Epub 2022 Aug 8. PMID: 35938715.

Ravel-Chapuis A, Duchesne E, Jasmin BJ. Pharmacological and exercise-induced activation of AMPK as emerging therapies for myotonic dystrophy type 1 patients. J Physiol. 2022 Jul;600(14):3249-3264. doi: 10.1113/JP282725. Epub 2022 Jun 28. PMID: 35695045.

Ravel-Chapuis A, Jasmin BJ. Combinatorial therapies for rescuing myotonic dystrophy type 1 skeletal muscle defects. Trends Mol Med. 2022 Jun;28(6):439-442. doi: 10.1016/j.molmed.2022.04.004. Epub 2022 May 7. PMID: 35537989.

Ravel-Chapuis A, Haghandish A, Daneshvar N, Jasmin BJ, Côté J. A novel CARM1-HuR axis involved in muscle differentiation and plasticity misregulated in spinal muscular atrophy. Hum Mol Genet. 2022 May 4;31(9):1453-1470. doi: 10.1093/hmg/ddab333. PMID: 34791230.